Process performance of cervical screening programmes in Europe
Autor: | Matejka Rebolj, Maja Primic Žakelj, Piret Veerus, Ofelia Suteu, Pär Sparén, Arkadiusz Chil, Ahti Anttila, Pamela Giubilato, Antonio Morais, Nikolaus Becker, Marjolein van Ballegooijen, Muriel Fender, Guglielmo Ronco, Juozas Kurtinaitis, Marian O’Reilly, Elsebeth Lynge, Lesz Lancucki |
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Přispěvatelé: | Public Health |
Rok vydání: | 2009 |
Předmět: |
Adult
Cancer Research medicine.medical_specialty Referral Uterine Cervical Neoplasms Young Adult SDG 3 - Good Health and Well-being Prevalence medicine Humans Mass Screening media_common.cataloged_instance European union Cervix Aged media_common Colposcopy Gynecology Cervical cancer Cervical screening medicine.diagnostic_test business.industry Incidence Attendance Middle Aged Uterine Cervical Dysplasia medicine.disease Europe Squamous intraepithelial lesion medicine.anatomical_structure Oncology Female business Demography |
Zdroj: | European Journal of Cancer, 45(15), 2659-2670. Elsevier Ltd. |
ISSN: | 0959-8049 |
DOI: | 10.1016/j.ejca.2009.07.022 |
Popis: | Standardised tables of aggregated data were collected from 15 European national or regional cervical screening programmes and key performance indicators computed as reported in European Union (EU) Guidelines, 2nd edition. Cytological results varied widely between countries both for the total proportion of abnormal tests (from 1.2% in Germany (Mecklenburg-Vorpommern) to 11.7% in Ireland-Midwest Region) and for their distribution by grade. Referral rates for repeat cytology (ranging from 2.9% of screened women in the Netherlands to 16.6% in Slovenia) or for colposcopy (ranging from 0.8% in Finland to 4.4% in Romania-Cluj) and the Positive Predictive Value (PPV) of colposcopic attendance (ranging from 8% in Romania-Cluj to 52% in Lithuania) were strongly influenced by management protocols, in particular for atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesion (LSIL) cytology. However, cytology-specific PPV also showed remarkable variability. The detection rate of CIN2+ histology ranged from 1% in England and Denmark. Low attendance for colposcopy after referral was observed in some east-European countries. These comparisons may be useful for improving the performance of cervical screening in general and more so if new screening technologies and vaccination for Human Papillomavirus are introduced. Overall, quality was better in countries that have operated organised programmes for a longer time, plausibly as a result of long-lasting monitoring and quality assurance activities. Therefore, the availability of these data, the first comparing European countries, and the increased number of countries that can provide such data (only five in 2004) represent progress. Nevertheless, there is a clear need to standardise the cytological and histological classifications used in screening, as well as data registration systems across Europe. (C) 2009 Elsevier Ltd. All rights reserved. |
Databáze: | OpenAIRE |
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