The Effect of Methylene Blue and Its Metabolite-Azure I-on Bioenergetic Parameters of Intact Mouse Brain Mitochondria

Autor:	A. P. Gureev, N. A. Samoylova, D. V. Potanina, V. N. Popov
Rok vydání:	2021
Předmět:	Clinical Biochemistry Molecular Medicine Biochemistry
Zdroj:	Biochemistry (Moscow) Supplement. Series B, Biomedical chemistry. 16(2)
ISSN:	1990-7508
Popis:	Methylene blue, a phenothiazine dye, that is widely used in medicine and is under clinical trials as an agent for treatment of Alzheimer's disease. One of the factors of the unique therapeutic effect of methylene blue is its redox properties, allowing implementation of alternative electron transport: the dye accepts electrons from reducing equivalents in mitochondria and transfer them to other components of the respiratory chain or molecular oxygen. Azure I, an
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ec748c35b1e111c199a9fba078f11c https://pubmed.ncbi.nlm.nih.gov/35601460 Zobrazit plný text záznamu Full text from SpringerLink