Congenital toxoplasmosis in France in 2007: first results from a national surveillance system
| Autor: | Villena, I., Ancelle, T., Delmas, C., Garcia, P., Brezin, A. P., Thulliez, P., Wallon, M., King, L., Goulet, V., Ajzenberg, Daniel, Dardé, Marie-Laure |
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| Přispěvatelé: | Université de Limoges (UNILIM), Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Resource Center (BRC) (CNR Toxoplasmose-Toxoplasma BRC), CHU Limoges, Neuroépidémiologie Tropicale et Comparée (NETEC), Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST FR CNRS 3503)-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Université de Limoges (UNILIM), Grelier, Elisabeth |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Pediatrics Epidemiology Abortion Toxoplasmosis Congenital MESH: Pregnancy Complications Parasitic MESH: Pregnancy Public health surveillance Pregnancy Risk Factors MESH: Risk Factors Prenatal Diagnosis MESH: Gestational Age Prevalence Medicine MESH: Incidence biology Incidence (epidemiology) Incidence MESH: Toxoplasma MESH: Infant Newborn MESH: Infant MESH: Infectious Disease Transmission Vertical Population Surveillance Female MESH: Abortion Induced France Toxoplasma Maternal Age medicine.medical_specialty Transplacental transmission Gestational Age MESH: Population Surveillance Virology Seroprevalence Humans MESH: Prenatal Diagnosis Fetal Death MESH: Prevalence MESH: Humans business.industry Public Health Environmental and Occupational Health Infant Newborn Toxoplasma gondii Infant Abortion Induced medicine.disease biology.organism_classification MESH: Toxoplasmosis Congenital Toxoplasmosis Infectious Disease Transmission Vertical MESH: Male Surgery MESH: France [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie Pregnancy Complications Parasitic MESH: Fetal Death MESH: Maternal Age [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business MESH: Female |
| Zdroj: | Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin, 2010, 15 (25), epub ahead of Europe PubMed Central |
| Popis: | International audience; When immunocompetent people become infected with the parasite Toxoplasma gondii, the disease is generally asymptomatic. However, transplacental transmission of T. gondii may lead to severe congenital infection including in utero abortion, foetal death, or neurological or ocular damage of the foetus. France has had a national programme to prevent congenital toxoplasmosis since 1978. However, although estimated seroprevalence in pregnant women has fallen from 84% in the 1960s to 44% in 2003, no reliable data have been available on the annual number of cases of congenital toxoplasmosis or the severity of infection. In 2006, the French National Institute for Public Health Surveillance (Institut de Veille Sanitaire) and the National Reference Centre for Toxoplasmosis recommended that a national laboratory-based surveillance system be used for the surveillance of the disease. In 2007, 31 laboratories reported at least one congenital case through the surveillance system, giving a total of 272 cases. A total of 11 terminations of pregnancy were reported (six abortions and five foetal deaths). Of the live-born cases, 206 were asymptomatic, 28 were symptomatic and seven had a severe form of the disease. As there were 818,700 births in France and French overseas departments in 2007, the overall prevalence of congenital toxoplasmosis observed that year was 3.3 (95% confidence interval (CI): 2.9 to 3.7) per 10,000 live births and the incidence rate of the disease at birth was 2.9 (95% CI: 2.5 to 3.2) per 10,000 live births; the estimated incidence rate of symptomatic congenital toxoplasmosis was 0.34 (95% CI: 0.2 to 0.5) cases per 10,000 live births. |
| Databáze: | OpenAIRE |
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