In Vivo Study on the Biocompatibility of Newly Developed Calcium Phosphate-Based Root Canal Sealers
| Autor: | Kwang-Shik Bae, Seung-Ho Baek, Jin-Su Kim |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Calcium Phosphates
Male Materials science Biocompatibility Root canal Dental Cements Dentistry chemistry.chemical_element Biocompatible Materials Calcium Apatite Rats Sprague-Dawley Root Canal Filling Materials chemistry.chemical_compound In vivo medicine Pulp canal Animals Zinc Oxide-Eugenol Cement General Dentistry Inflammation business.industry Rats medicine.anatomical_structure chemistry Connective Tissue visual_art Zinc oxide eugenol visual_art.visual_art_medium business Subcutaneous tissue |
| Zdroj: | Journal of Endodontics. 30:708-711 |
| ISSN: | 0099-2399 |
| Popis: | This study compared the biocompatibility of two new calcium phosphate-based root canal sealers (CAPSEAL I, CAPSEAL II) with another type of commercially available calcium phosphate sealer (Apatite Root Sealer type I, Apatite Root Sealer type II) and a zinc oxide eugenol-based sealer (Pulp Canal Sealer EWT) after implanting them in the subcutaneous tissue of rats. After 1, 2, 4, and 12 weeks, the tubes were removed with the surrounding tissues. The tissue reactions were graded as being mild or 1, moderate or 2, and severe or 3 after a histopathological examination. The results were analyzed statistically with the Kruskal-Wallis test. The biocompatibility of the materials was interpreted according to the Federation Dentaire Internationale criteria (1980). The inflammatory reactions decreased with time. The new sealers showed a lower tissue response than any of the other sealers in all the experimental periods. All the tested sealers showed an acceptable biocompatibility. |
| Databáze: | OpenAIRE |
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