Nonsteroidal anti‐inflammatory drugs associated acute kidney injury in hospitalized children: A systematic review and meta‐analysis

Autor: Mengya Li, Jun Gong, Chaoyang Chen, Simiao Zhao, Yimin Cui, Lingyue Ma, Lingyun Ma, Ying Zhou
Rok vydání: 2021
Předmět:
Zdroj: Pharmacoepidemiology and Drug Safety. 31:117-127
ISSN: 1099-1557
1053-8569
4202-1219
Popis: INTRODUCTION Nonsteroidal anti-inflammatory drugs (NSAIDs) are regarded as nephrotoxins. Children commonly use NSAIDs and are susceptible to nephropathy, but the relationship between acute kidney injury (AKI) and use of NSAIDs is not well examined yet. OBJECTIVE To evaluate the relationship between AKI and use of NSAIDs in hospitalized pediatric patients who are susceptible to nephropathy. METHODS We conducted this systematic review and meta-analysis of observational studies by searching PubMed, Embase, and Cochrane Database for articles published up to June 1, 2020. Reports included involved children (age
Databáze: OpenAIRE