Nonsteroidal anti‐inflammatory drugs associated acute kidney injury in hospitalized children: A systematic review and meta‐analysis
Autor: | Mengya Li, Jun Gong, Chaoyang Chen, Simiao Zhao, Yimin Cui, Lingyue Ma, Lingyun Ma, Ying Zhou |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Adolescent Epidemiology Nephropathy chemistry.chemical_compound Internal medicine Odds Ratio Humans Medicine Pharmacology (medical) Child Nonsteroidal business.industry Anti-Inflammatory Agents Non-Steroidal Acute kidney injury Outcome measures Odds ratio Acute Kidney Injury medicine.disease digestive system diseases Confidence interval Observational Studies as Topic Pharmaceutical Preparations chemistry Meta-analysis Observational study business Child Hospitalized |
Zdroj: | Pharmacoepidemiology and Drug Safety. 31:117-127 |
ISSN: | 1099-1557 1053-8569 4202-1219 |
Popis: | INTRODUCTION Nonsteroidal anti-inflammatory drugs (NSAIDs) are regarded as nephrotoxins. Children commonly use NSAIDs and are susceptible to nephropathy, but the relationship between acute kidney injury (AKI) and use of NSAIDs is not well examined yet. OBJECTIVE To evaluate the relationship between AKI and use of NSAIDs in hospitalized pediatric patients who are susceptible to nephropathy. METHODS We conducted this systematic review and meta-analysis of observational studies by searching PubMed, Embase, and Cochrane Database for articles published up to June 1, 2020. Reports included involved children (age |
Databáze: | OpenAIRE |
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