The thioamidation of gem-dibromoalkenes in an aqueous medium

Autor:	Ankush Gupta, Jaydeepbhai P Jadav, Guddeangadi N Gururaja, Jigarkumar K Vankar, Shankara H Nanjegowda
Rok vydání:	2021
Předmět:	chemistry.chemical_classification chemistry Aqueous medium Organic Chemistry chemistry.chemical_element Organic chemistry Amine gas treating Physical and Theoretical Chemistry Selectivity Biochemistry Sulfur Thioamide Catalysis
Zdroj:	Organic & Biomolecular Chemistry. 19:2473-2480
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d0ob02319a
Popis:	The direct integration of sulphur and amine groups with 1,1-dibromoalkenes for thioamide synthesis has been achieved in an aqueous medium. The presented green protocol emphasizes the suitability of aqueous media for the thioamidation reaction and enables greater selectivity with synthetic utility. A wide range of thioamides in moderate to excellent yields has been achieved using readily available starting materials, with the use of no organic solvents, catalysts, or additives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c7c62c2e69cb33f18093725fe146d3 https://doi.org/10.1039/d0ob02319a Zobrazit plný text záznamu