A higher glycemic response to oral glucose is associated with higher plasma apolipoprotein C3 independently of BMI in healthy twins
| Autor: | Kirsi H. Pietiläinen, Marja-Riitta Taskinen, Aila Rissanen, Jaakko Kaprio, Bram J. Berntzen, Lutgarda Bozzetto |
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| Přispěvatelé: | CAMM - Research Program for Clinical and Molecular Metabolism, Research Programs Unit, Faculty of Medicine, University of Helsinki, Institute for Molecular Medicine Finland, Department of Public Health, HUS Abdominal Center, Department of Medicine, Clinicum, Endokrinologian yksikkö, Bozzetto, Lutgarda, Berntzen, Bram J., Kaprio, Jaakko, Rissanen, Aila, Marja-Riitta, Taskinen, Pietiläinen, Kirsi H. |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Blood Glucose
Male Very low-density lipoprotein Time Factors Endocrinology Diabetes and Metabolism Medicine (miscellaneous) Type 2 diabetes 030204 cardiovascular system & hematology Body fat percentage Body Mass Index chemistry.chemical_compound 0302 clinical medicine Risk Factors PLASMA TRIGLYCERIDE Finland Adiposity 2. Zero hunger Glucose metabolism Nutrition and Dietetics Healthy Volunteers TWINS Female Apolipoprotein C3 Cardiology and Cardiovascular Medicine Twins Adult medicine.medical_specialty education 030209 endocrinology & metabolism 03 medical and health sciences Young Adult Internal medicine medicine Humans Obesity Triglycerides Glycemic Glucose Metabolism Disorders Apolipoprotein C-III Triglyceride business.industry Cholesterol Twins Monozygotic Glucose Tolerance Test medicine.disease Endocrinology chemistry 3121 General medicine internal medicine and other clinical medicine business Body mass index Biomarkers |
| Popis: | Plasma apolipoprotein C3 (ApoC3) is associated with higher plasma triglyceride and type 2 diabetes incidence. We evaluated whether body mass index (BMI) or glucose metabolism were associated with ApoC3 in healthy monozygotic (MZ) twins. Forty-seven MZ twin-pairs (20 man, 27 women), aged 23-42 years, were divided in subgroups according to discordance or concordance for (a) BMI (within-pair difference (Δ) in BMI≥3.0 or |
| Databáze: | OpenAIRE |
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