Impact on Health-Related Quality of Life of Video-Assisted Thoracoscopic Surgery for Lung Cancer
Autor: | Clare Evans, Doug West, Kerry N L Avery, Timothy J.P. Batchelor, Katy A Chalmers, Rakesh Krishnadas, Jane M Blazeby, Gianluca Casali, Eveline Internullo |
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Rok vydání: | 2019 |
Předmět: |
Male
medicine.medical_specialty Lung Neoplasms Constipation medicine.medical_treatment 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Surgical oncology Carcinoma Non-Small-Cell Lung Surveys and Questionnaires medicine Humans Prospective Studies Thoracic Oncology Lung cancer Prospective cohort study Fatigue Aged Neoplasm Staging Aged 80 and over Health related quality of life Pain Postoperative Lung cancer surgery Thoracic Surgery Video-Assisted business.industry Middle Aged medicine.disease humanities United Kingdom 3. Good health Surgery Thoracotomy Oncology 030220 oncology & carcinogenesis Social function Video-assisted thoracoscopic surgery Quality of Life Female medicine.symptom business |
Zdroj: | Annals of Surgical Oncology |
ISSN: | 1534-4681 1068-9265 |
DOI: | 10.1245/s10434-019-08090-4 |
Popis: | Background Video-assisted thoracoscopic surgery (VATS) approaches are increasingly used in lung cancer surgery, but little is known about their impact on patients’ health-related quality of life (HRQL). This prospective study measured recovery and HRQL in the year after VATS for non-small cell lung cancer (NSCLC) and explored the feasibility of HRQL data collection in patients undergoing VATS or open lung resection. Patients and Methods Consecutive patients referred for surgical assessment (VATS or open surgery) for proven/suspected NSCLC completed HRQL and fatigue assessments before and 1, 3, 6 and 12 months post-surgery. Mean HRQL scores were calculated for patients who underwent VATS (segmental, wedge or lobectomy resection). Paired t-tests compared mean HRQL between baseline and expected worst (1 month), early (3 months) and longer-term (12 months) recovery time points. Results A total of 92 patients received VATS, and 18 open surgery. Questionnaire response rates were high (pre-surgery 96–100%; follow-up 67–85%). Pre-surgery, VATS patients reported mostly high (good) functional health scores [(European Organisation for Research and Treatment of Cancer) EORTC function scores > 80] and low (mild) symptom scores (EORTC symptom scores Conclusions Lung resection has a considerable detrimental impact on patients’ HRQL that is not fully resolved 12 months post-surgery, despite a VATS approach. Graphic Abstract |
Databáze: | OpenAIRE |
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