Pair-wise linear and 3D nonlinear relationships between the liver antioxidant enzyme activities and the rate of body oxygen consumption in mice
| Autor: | Utko Na, V.V. Bezrukov, Alexander Y Litoshenko, Pishel' In, Vadim E Fraifield, T. G. Mozzhukhina, Khachik K. Muradian |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Antioxidant medicine.medical_treatment Body oxygen consumption Biochemistry Antioxidants Superoxide dismutase Mice Oxygen Consumption Physiology (medical) Internal medicine Linear regression medicine Animals chemistry.chemical_classification Glutathione Peroxidase biology Superoxide Dismutase Glutathione peroxidase Catalase Endocrinology Enzyme Pair wise chemistry Liver Nonlinear Dynamics biology.protein Linear Models Mice Inbred CBA Female human activities circulatory and respiratory physiology |
| Zdroj: | Free radical biologymedicine. 33(12) |
| ISSN: | 0891-5849 |
| Popis: | Relationships between the rate of body oxygen consumption (VO2) and the liver key antioxidant enzyme activities were assessed in female CBA mice. The pair-wise linear regression and correlation demonstrated significant correlative links between VO2 and activity of catalase (CAT). Nonlinear 3D plotting revealed a complementary pattern of CAT and glutathione peroxidase (GP) relation. CAT activity was elevated in mice with proportionally high VO2 and superoxide dismutase (SOD), whereas GP activity was high in animals with low or disproportional VO2 and SOD. |
| Databáze: | OpenAIRE |
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