Misoprostol versus expectant management in women with incomplete first‐trimester miscarriage after failed primary misoprostol treatment: A randomized clinical trial
| Autor: | Samar M Emam, Mohammed K. Ali, Mahmoud A Abdel-Aleem, Ahmed M A Sobh |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Incomplete miscarriage
medicine.medical_specialty Miscarriage law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Pregnancy Complete miscarriage law Humans Medicine 030212 general & internal medicine Watchful Waiting Adverse effect Misoprostol Expectant management Abortifacient Agents Nonsteroidal 030219 obstetrics & reproductive medicine business.industry Obstetrics Obstetrics and Gynecology General Medicine medicine.disease Abortion Incomplete Abortion Spontaneous Pregnancy Trimester First First trimester Treatment Outcome Female business medicine.drug |
| Zdroj: | International Journal of Gynecology & Obstetrics. 154:558-564 |
| ISSN: | 1879-3479 0020-7292 |
| DOI: | 10.1002/ijgo.13652 |
| Popis: | OBJECTIVE To compare the effectiveness and safety of repeat misoprostol versus expectant management in women with first-trimester incomplete miscarriage who have been initially treated with misoprostol. METHODS The study was an open-labeled randomized controlled trial including women with an incomplete first-trimester miscarriage after administration of misoprostol. The participants were randomly assigned to vaginal misoprostol or expectant management using a computer-generated table of random numbers. The primary outcome was the number of women with a complete miscarriage at 1 week. RESULTS Eighty-eight women (44 women in each group) were analyzed. The rate of complete miscarriage at 1 week was significantly higher in the misoprostol group than the expectant management group-29 (69.0%) versus 7 (16.7%) (P |
| Databáze: | OpenAIRE |
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