The Impact of Human Parvovirus B19 Infection on Heart Failure and Anemia with Reference to Iron Metabolism Markers in an Adult Woman
| Autor: | Mayumi Tsuji, Yusuke Dodo, Isao Ohsawa, Hiromichi Gotoh, Masahiro Inagaki, Yuji Kiuchi, Yoshikazu Goto, Yuya Nakamura, Hokuto Namba |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult medicine.medical_specialty Anemia Pleural effusion Iron Case Report Gastroenterology Parvoviridae Infections growth differentiation factor-15 03 medical and health sciences Internal medicine Edema hemic and lymphatic diseases erythroferrone Internal Medicine medicine Parvovirus B19 Human Humans human parvovirus B19 Heart Failure Anemia Iron-Deficiency business.industry General Medicine Iron deficiency Erythroferrone medicine.disease Rash anemia 030104 developmental biology Treatment Outcome Heart failure Immunology Female GDF15 medicine.symptom business hepcidin-25 |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 |
| Popis: | A 35-year-old woman with fever, edema and rash was admitted. Pleural effusion and cardiomegaly were observed. A laboratory analysis revealed anemia with iron deficiency and elevated human parvovirus B19 (B19V) immunoglobulin M. The patient's hepcidin-25 and erythroferrone levels were not elevated compared to those observed later in her clinical course. On the other hand, her growth differentiation factor-15 (GDF-15) levels were elevated. She was diagnosed to have heart failure symptoms and anemia with specific iron metabolism abnormalities due to a B19V infection. After providing supportive treatment, the heart failure symptoms disappeared and her anemia had improved. This case emphasizes the need to include a B19V infection in the differential diagnosis when we encounter cases demonstrating reversible heart failure with anemia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|