Determination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015
| Autor: | M. Dilek Avsaroglu, Yeşim Soyer, Mustafa Guzel |
|---|---|
| Přispěvatelé: | [Belirlenecek] |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.drug_class
Microorganism Antibiotics [No Keywords] Biology Food Science and Technology medicine.disease_cause Gıda Bilimi ve Teknolojisi Microbiology Multiple drug resistance Minimum inhibitory concentration Antimicrobial resistance Colistin Escherichia coli Antibiotic resistance Colistin medicine Gene Escherichia coli medicine.drug |
| Zdroj: | Volume: 6, Issue: 3 160-169 Food and Health |
| ISSN: | 2602-2834 |
| Popis: | Antimicrobial resistance of pathogenic microorganisms is an emerging public health concern. Intensive use of antibiotics in food animals might increase antimicrobial resistance in foodborne pathogens. Colistin is a last resort antibiotic for treatment of multidrug resistant (MDR) Gram negative pathogens. The recent antimicrobial resistance studies revealed a mobile antimicrobial resistance gene (mcr) that provides resistance to colistin. Furthermore, the gene has been found in different genera. Therefore, the aim of this study was to determine colistin resistance of Escherichia coli isolates (N=48) isolated in between 2011 and 2015 from food samples in Turkey. In addition, 5 mcr genes and their variants were screened by performing PCR on resistant isolates. 4 E. coli isolates were found resistant to colistin above the epidemiological cut-off value (Minimum inhibitory concentration (MIC) > 2mg/L). None of the resistant isolates had the mcr genes. Further studies with human and food isolates should be conducted to figure out which gene or genes are responsible for colistin resistance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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