Prevalence of Barrett’s esophagus in obese patients undergoing pre-bariatric surgery evaluation: a systematic review and meta-analysis
| Autor: | Alexander L. Ayzengart, Sherif Gendy, Peter V. Draganov, Dennis Yang, Alexander Wallace, Davis Estores, Bashar J. Qumseya |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Esophageal Neoplasms Bariatric Surgery Barrett Esophagus 03 medical and health sciences 0302 clinical medicine Prevalence Humans Medicine Risk factor medicine.diagnostic_test business.industry Esophagogastroduodenoscopy Gastroenterology Publication bias medicine.disease Confidence interval Obesity Morbid Surgery 030220 oncology & carcinogenesis Barrett's esophagus Meta-analysis GERD 030211 gastroenterology & hepatology business Body mass index |
| Zdroj: | Endoscopy. 52:537-547 |
| ISSN: | 1438-8812 0013-726X |
| Popis: | Introduction Obesity is a known risk factor for gastroesophageal reflux disease (GERD), Barrett’s esophagus (BE), and esophageal adenocarcinoma (EAC). Obese patients routinely undergo preoperative esophagogastroduodenoscopy (EGD) before bariatric procedures. We aimed to assess the prevalence of BE in this patient population. Methods We conducted a comprehensive literature search ending in March 2019. Search results were imported into covidence.org and screened by two independent reviewers. Heterogeneity was assessed using I 2 and Q statistics and publication bias using funnel plots and the Orwin fail-safe test. Random-effects modeling was used in all analyses. Results Of 4087 citations, 77 were reviewed in full text and 29 were included in the final analysis based on our predetermined inclusion/exclusion criteria. A total of 13 434 patients underwent pre-bariatric surgery EGD. The pooled prevalence of BE using random-effects modeling was 0.9 % (95 % confidence interval [CI] 0.7 % – 1.3 %); P Conclusions Obesity has been postulated as a major risk factor for BE, yet we found that the prevalence of BE in morbidly obese patients undergoing preoperative EGD was very low. Therefore, obesity alone may not be a major risk factor for BE. |
| Databáze: | OpenAIRE |
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