Assessing Patient Preferences for Intestinal Failure Management Using the Time Trade-Off Methodology

Autor: Cherry E. Koh, Sharon Carey, Wendy Tu, Lynn Hyde-Jones
Rok vydání: 2018
Předmět:
Adult
Male
medicine.medical_specialty
030309 nutrition & dietetics
Medicine (miscellaneous)
Time-trade-off
Teduglutide
Health Services Accessibility
Cohort Studies
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Quality of life (healthcare)
Gastrointestinal Agents
Intestinal failure
Surveys and Questionnaires
Activities of Daily Living
Intestine
Small
medicine
Humans
Intensive care medicine
Aged
0303 health sciences
Nutrition and Dietetics
business.industry
Australia
Disease Management
Patient Preference
Organ Transplantation
Middle Aged
Patient preference
Transplantation
Intestines
Intestinal Diseases
Parenteral nutrition
Cross-Sectional Studies
Treatment Outcome
chemistry
Cohort
Quality of Life
030211 gastroenterology & hepatology
Female
Quality-Adjusted Life Years
business
Parenteral Nutrition
Home
Peptides
Zdroj: JPEN. Journal of parenteral and enteral nutritionReferences. 43(7)
ISSN: 1941-2444
Popis: Background There are limited management options available for people with Type III intestinal failure (IF), with home parenteral nutrition (HPN) being the main treatment option. The aim of this research is to compare patient preferences in managing Type III IF using time trade-off (TTO) methodology and to determine which factors have the greatest impact on health-related quality of life (HRQoL). Methods An interviewer-administered telephone survey was conducted on a cross-sectional cohort of 19 HPN participants. The survey was designed to measure HRQoL using a TTO methodology. Four different treatment options were presented, and participants decided how many years of life they would trade to have access to the treatment and hence a different health state. The 4 scenarios included reduction in line infections, optimization of care, small bowel growth (teduglutide), and intestinal transplantation. Health state utility scores were calculated. Results The median health utility score for optimization of care and small bowel growth (teduglutide) were lowest (0.5; range 0-1) meaning a greater desire for this treatment. Intestinal transplant had the highest median utility score (1.0; range 0-1) indicating less willingness for this treatment option. Conclusions This is the first known study to use TTO methodology assessing treatment options in people with IF requiring HPN. Results indicate people requiring HPN make careful decisions when considering treatment options. Facilities providing HPN services should focus on optimization of current care, which is highly valued by their patients.
Databáze: OpenAIRE
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