Bimodal Expression Patterns, and Not Viral Burst Sizes, Predict the Effects of Vpr on HIV-1 Proviral Populations in Jurkat Cells
| Autor: | Edmond Atindaana, Abena Kissi-Twum, Sarah Emery, Cleo Burnett, Jake Pitcher, Myra Visser, Jeffrey M. Kidd, Alice Telesnitsky |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | mBio. 13 |
| ISSN: | 2150-7511 |
| Popis: | A bedrock assumption in HIV-1 population modeling is that all active cells release the same amount of virus. However, the findings here revealed that when HIV-infected cells expand into clones, each clone differs in virus production. |
| Databáze: | OpenAIRE |
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