Psychiatric and hostility factors related to use of anabolic steroids in monozygotic twins
| Autor: | Thomas A Pagonis, Paraskevi N. Toli, Christos Hadjichristodoulou, Nikiforos V. Angelopoulos, George N. Koukoulis |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male 030213 general clinical medicine medicine.medical_specialty Time Factors Psychometrics Substance-Related Disorders Monozygotic twin Poison control Hostility Anxiety 03 medical and health sciences Anabolic Agents 0302 clinical medicine Surveys and Questionnaires Injury prevention medicine Humans Psychiatry Paranoid Behavior Doping in Sports Psychiatric Status Rating Scales Mental Disorders Testosterone (patch) Twins Monozygotic 030229 sport sciences Aggression Psychiatry and Mental health Steroids Observational study medicine.symptom Psychology Stress Psychological Psychopathology |
| Zdroj: | European Psychiatry. 21:563-569 |
| ISSN: | 1778-3585 0924-9338 |
| Popis: | IntroductionAnabolic androgenic steroids (AAS) are derived by chemical manipulation of the testosterone molecule. The specified category of drugs produces anabolic, androgenic and psycho-active effects including elevated aggressive, hostile, violent and anti social behavior.ObjectiveThe objective of this case report observational study was to evaluate the possible psychological consequences of AS use in the twin user of each pair, compared with the non-user twin.MethodologyWe studied two pairs of male monozygotic twins: one pair 24 years old and the other 31 years old, with absolute genome and phenotype similarity. One of the twins of each pair used AAS while the other did not. Both pairs lived in Hellenic provincial towns and followed a common training and nutrition regime. The psychometric instruments used were the Symptoms Check List-90 (SCL-90) and the Hostility and Direction of Hostility Questionnaire (HDHQ). The psychometric evaluations took place within a time interval of 6 months.ResultsThe study found high levels of aggressiveness, hostility, anxiety and paranoid ideation in the twins who used AS. The non-user twins showed no deviation from their initial status.ConclusionThe use of AAS induced several important psychiatric changes in monozygotic twins which were not present in the twin who did not use AAS. |
| Databáze: | OpenAIRE |
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