Asymmetric aldol condensation as a route to polypropionate derived pheromones
| Autor: | James P. DiBattista, Francis X. Webster |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Magnetic Resonance Spectroscopy
Spectrophotometry Infrared Stereochemistry Clinical Biochemistry Pharmaceutical Science Biochemistry Pheromones Adduct Drug Discovery Valerates Stegobinone Organic chemistry Sitophilure Molecular Biology Chemistry Organic Chemistry Sitophilate Stereoisomerism Ketones Pyrones Sex pheromone Molecular Medicine Pheromone Aldol condensation Propionates Serricornin |
| Zdroj: | Bioorganic & Medicinal Chemistry. 4:423-428 |
| ISSN: | 0968-0896 |
| DOI: | 10.1016/0968-0896(96)00021-1 |
| Popis: | The synthesis of the polypropionate-derived pheromones sitophilate (1) and sitophilure (2) are described using an asymmetric aldol condensation as the key step to adduct 6; compound 6 was smoothly converted to the antipodes of each pheromone. This procedure can be expanded to more complicated structures with the same type of syn configuration such as stegobinone (3) and serricornin (4). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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