Diagnostic value OF oct-angiography AND regional hemodynamic assesSment in patients with retinal vein occlusion
| Autor: | Aleksey G. Rukhovets, Aleksandra I. Titarenko, Yury S. Astakhov, Svetlana Nikolaevna Tultseva |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Retinal Vein oct-angiography genetic structures Ischemia Hemodynamics Microcirculation capillary perfusion lcsh:Ophthalmology Ophthalmology ocular blood flow Occlusion Medicine In patient ophthalmoplethysmography General Environmental Science medicine.diagnostic_test business.industry retinal ischemia Anatomy Blood flow medicine.disease Fluorescein angiography eye diseases retinal vein occlusions lcsh:RE1-994 General Earth and Planetary Sciences sense organs business |
| Zdroj: | Офтальмологические ведомости, Vol 10, Iss 2, Pp 40-48 (2017) |
| ISSN: | 2412-5423 1998-7102 |
| Popis: | Introduction. Ischemic maculopathy is the main cause of irreversible vision loss due to retinal vein occlusion (RVO). Fluorescein angiography (FA), which is the gold standard for evaluating retinal capillary plexuses, does not allow for the visualization of separate intraretinal capillary networks. Optical coherence tomography angiography (OCT-angiography) enables the possible visualization of four capillary plexi and allows for the quantitative analysis of microcirculation to quantitatively estimate capillary network density and non-perfusion areas. Aim. To investigate microcirculation changes using OCT-angiography data and to compare the changes with opthalmoplethysmography indices in patients with RVO. Material and methods. The study included 12 patients with RVO. In all patients, a routine ophthalmic examination was performed, and ocular blood flow was estimated using FA, OCT-angiography, and ophthalmoplethysmography. Results. Ischemia in the macular area was detected in four patients (25%) according to FA results, and in eight (67%) accor ding to OCT-angiography data. Compared with the unaffected eye, significant decrease in the density of both superficial and deep capillary plexuses as well as a decrease in flow area and enlargement of foveal avascular zone were observed. A significant close direct correlation was established between capillary density in the superficial capillary plexus (r 0.8) and the deep capillary plexus (r 0.7), choroidal thickness, and opthalmoplethysmography indices (r 0.6). Conclusion. Compared with FA, OCT-angiography is a more sensitive method to detect macular capillary perfusion. In cases with RVO, the combination of the above mentioned methods with ophthalmoplethysmography allows for the comprehensive evaluation of regional hemodynamics. |
| Databáze: | OpenAIRE |
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