Nonalcoholic fatty pancreas disease: An emerging clinical challenge
| Autor: | Jian-Ning Li, Jing-Jiao Wang, Yi Yang, Cheng-Lei Zhang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pancreatic disease
business.industry Review General Medicine Type 2 diabetes Disease medicine.disease Bioinformatics Metabolic syndrome Nonalcoholic fatty pancreatic disease Pancreatic steatosis Pancreatic fistula Pancreatic cancer Nonalcoholic fatty liver disease medicine Pancreatitis Obesity business Pancreas |
| Zdroj: | World Journal of Clinical Cases |
| ISSN: | 2307-8960 |
| DOI: | 10.12998/wjcc.v9.i23.6624 |
| Popis: | Nonalcoholic fatty pancreas disease (NAFPD) is an emerging disease that has gained an increasing amount of attention in recent years. It describes fat accumulation in the pancreas with insignificant alcohol consumption, but the pathogenesis is largely unknown. A wide range of terms have been used to describe the phenomenon of pancreatic fat accumulation, but NAFPD remains an under-recognized and non-independent disorder. Obesity, age, sex, race, and unhealthy lifestyle are established independent risk factors for NAFPD, which is strongly associated with metabolic syndrome, type 2 diabetes, pancreatitis, pancreatic fistula, pancreatic cancer, and nonalcoholic fatty liver disease. At present, imaging techniques are common diagnostic aids, but uniform criteria and consensus are lacking. Therapeutically, healthy diet, weight loss, and exercise are the mainstays to reduce pancreatic fat accumulation. It can be seen that there is a limited understanding of NAFPD at this stage and further exploration is needed. Previous studies have revealed that NAFPD may directly affect diagnosis and clinical decision-making. Therefore, exploring the pathophysiological mechanism and clinical associations of NAFPD is a major challenge for researchers and clinicians. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|