Molecular and Cellular Biology, 24(24), 10670-10680. American Society for Microbiology
ISSN:
0270-7306
DOI:
10.1128/mcb.24.24.10670-10680.2004
Popis:
XPG is the human endonuclease that cuts 3' to DNA lesions during nucleotide excision repair. Missense mutations in XPG can lead to xeroderma pigmentosum (XP), whereas truncated or unstable XPG proteins cause Cockayne syndrome (CS), normally yielding life spans of