Scanning electron microscopy and biochemical studies on reconstituted and native chromatin fractions of novikoff hepatoma ascites cells
| Autor: | Yerach Daskal, Harris Busch, N.R. Ballal |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Novikoff Hepatoma
Transcriptional activity Transcription Genetic Chromosomal Proteins Non-Histone Scanning electron microscope DNA Cell Biology Biology Molecular biology Chromatin Cell Line Histones chemistry.chemical_compound chemistry Biochemistry Ascites Microscopy Electron Scanning medicine medicine.symptom |
| Zdroj: | Experimental Cell Research. 108:301-309 |
| ISSN: | 0014-4827 |
| DOI: | 10.1016/s0014-4827(77)80037-2 |
| Popis: | Summary Scanning electron microscopic and biochemical studies of native and the various fractions of reconstituted chromatin of Novikoff hepatoma ascites cells demonstrated structural differences between the native and reconstituted chromatins. No significant differences were detected between the transcriptional activity of native or reconstituted chromatin. However, the morphology of these two fractions differed with respect to the abundance of exposed DNA filaments. “Naked” DNA fibers were abundant in DNA-histone complexes, these complexes were transcriptionally inactive. |
| Databáze: | OpenAIRE |
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