Biological subtypes of breast cancer and sentinel lymph node biopsy
| Autor: | Mehmet Ali Gülçelik, Gökhan Giray Akgül, Lutfi Dogan, Erhan H Güven, Muhammet Kadri Çolakoğlu |
|---|---|
| Přispěvatelé: | RTEÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Çolakoğlu, Muhammet Kadri |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Sentinel lymph node Group ii medicine.disease Gastroenterology 03 medical and health sciences 0302 clinical medicine Breast cancer 030220 oncology & carcinogenesis Internal medicine Biopsy medicine Original Article In patient 030212 general & internal medicine B subgroup business Triple negative Combined method Cerrahi |
| Popis: | Objective: Breast cancer subtypes are used as prognostic and predictive factors considering the genomic profile of the disease. This study is designed to investigate the Sentinel Lymph Node (SLN) detection rate in breast cancer for different biological characteristics. Material and Methods: Patients on whom we performed the methylene blue method alone were named as Group I, radiocolloid substance method alone as Group II and both methylene blue and radiocolloid method as Group III. The results of biological tumor characteristics and characteristics of the patients on different SLN biopsy techniques were investigated. Results: The overall SLN detecting success rate was 83.3%. When considered for each group, success rate was 80% for group I, 84.9% for group II and 90.6% for group III. While a success rate of 94.6% was achieved with radiocolloid only in the patients in Luminal A and B subgroup, 90% success rate was achieved in Her2 (+) and triple negative (TN) patients with combined method. Conclusion: While successful results could be achieved by using radiocolloid substances alone in patients with Luminal A and B subtypes, combined methods should be used in HER2 (+) and TN patients |
| Databáze: | OpenAIRE |
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