Outcome After Surgery for Acute Aortic Dissection: Influence of Preoperative Antiplatelet Therapy on Prognosis
| Autor: | Raphaelle Avigael Chemtob, Hanne Berg Ravn, Peter Skov Olsen, Hasse Moeller-Soerensen, Lene Holmvang |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Blood Loss Surgical 030204 cardiovascular system & hematology 03 medical and health sciences Postoperative Complications 0302 clinical medicine Transfusion requirement Preoperative Care medicine Humans 030212 general & internal medicine Acute Coronary Syndrome Aged Retrospective Studies Aortic dissection business.industry Perioperative Middle Aged Prognosis medicine.disease University hospital Clopidogrel Aortic Aneurysm Surgery Aortic Dissection Treatment Outcome Anesthesiology and Pain Medicine Female Fresh frozen plasma Cardiology and Cardiovascular Medicine business Ticagrelor Platelet Aggregation Inhibitors medicine.drug |
| Zdroj: | Journal of Cardiothoracic and Vascular Anesthesia. 31:569-574 |
| ISSN: | 1053-0770 |
| DOI: | 10.1053/j.jvca.2016.10.007 |
| Popis: | Objectives Outcome in patients with acute coronary syndrome (ACS) is improved with dual antiplatelet therapy (DAPT). Patients with acute aortic dissection type A (AAD) often present with similar symptoms and may therefore be prescribed DAPT before diagnosis. The aim of this study was to evaluate the use of antiplatelet therapy (APT) prior to AAD surgery and patient outcome, including indications according to the European Society of Cardiology’s (ESC) recent guidelines. Design A retrospective, observational study. Setting A tertiary University Hospital, Rigshospitalet, Heart Centre, Copenhagen, Denmark. Participants The study included 171 patients operated for AAD during 2010 to 2014. Interventions The independent relationship of preoperative APT was explored on 30-day mortality, intraoperative bleeding and perioperative transfusion requirements. Furthermore, the indications for APT were obtained. Measurements and Main Results Patients receiving APT (n = 73) did not have an increased 30-day mortality (29% v 20%, p = 0.18). However, APT increased intraoperative bleeding by 45% (p |
| Databáze: | OpenAIRE |
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