Effects of Different Cognitive Trainings on Amnestic Mild Cognitive Impairment in the Elderly: A One-Year Longitudinal Functional Magnetic Resonance Imaging (MRI) Study
| Autor: | Xinyi Cao, Guopu Wang, Lijuan Jiang, Chunbo Li, Xiaoliang Gong, Wei Feng, Gengdan Hu, Long Tang, Dan Wang, Yan Cheng |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Mild Cognitive Impairment medicine.medical_specialty Middle temporal gyrus Precuneus Superior parietal lobule Audiology 03 medical and health sciences 0302 clinical medicine Clinical Research Inferior temporal gyrus medicine Humans Middle frontal gyrus Cognitive Dysfunction Longitudinal Studies cardiovascular diseases Gray Matter Aged Brain Mapping Fusiform gyrus Cognitive Behavioral Therapy 030214 geriatrics medicine.diagnostic_test business.industry Age Factors Brain Precentral gyrus General Medicine Magnetic Resonance Imaging medicine.anatomical_structure Cognitive Therapy nervous system cardiovascular system Female Amnesia Functional magnetic resonance imaging business 030217 neurology & neurosurgery |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| DOI: | 10.12659/msm.908315 |
| Popis: | BACKGROUND Cognitive training has been focused on the interventions of amnestic mild cognitive impairment (aMCI) in recent years, with poor understanding. MATERIAL AND METHODS The study participants with aMCI were screened in a previous intervention trial. Functional magnetic resonance imaging (fMRI) was adopted to investigate effects of single-domain cognitive training (SDCT) and multi-domain cognitive training (MDCT) on aMCI and to explore potential mechanisms. RESULTS There were significant differences in the grey matter volume of the middle frontal gyrus, superior parietal lobule, inferior temporal gyrus, fusiform gyrus, and ventral V3 between the MDCT/SDCT group and the control group (P |
| Databáze: | OpenAIRE |
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