The impact of frequent cystoscopy on surgical care and cancer outcomes among patients with low‐risk, non–muscle‐invasive bladder cancer
| Autor: | Douglas J. Robertson, Philip P. Goodney, Kristine E. Lynch, Todd A. MacKenzie, David S. Han, Brenda E. Sirovich, John D. Seigne, Zhongze Li, Florian R. Schroeck |
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| Rok vydání: | 2019 |
| Předmět: |
Cancer Research
medicine.medical_specialty Bladder cancer medicine.diagnostic_test business.industry Surgical care Urology Cancer Retrospective cohort study Cystoscopy medicine.disease Cystoscopies Article 03 medical and health sciences 0302 clinical medicine Oncology 030220 oncology & carcinogenesis medicine 030212 general & internal medicine business Non muscle invasive Veterans Affairs |
| Zdroj: | Cancer |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/cncr.32185 |
| Popis: | BACKGROUND: Surveillance recommendations for patients with low-risk non-muscle-invasive bladder cancer (NMIBC) are based on limited evidence. Our objective was to add to the evidence by assessing outcomes after frequent versus recommended cystoscopic surveillance. METHODS: This is a retrospective cohort study of patients diagnosed with low-risk (low grade Ta) NMIBC from 2005 – 2011 with follow-up through 2014 from the Department of Veterans Affairs. Patients were classified as having undergone frequent versus recommended cystoscopic surveillance (>3 versus 1–3 cystoscopies in the first 2 years after diagnosis). Using propensity score adjusted models, we estimated the impact of frequent cystoscopy on the number of transurethral resections, the number of resections without cancer in the specimen, and on risk of progression to muscle-invasive cancer or bladder cancer death. RESULTS: Among 1,042 patients, 798 (77%) had more frequent cystoscopy than recommended. In adjusted analyses, the frequent cystoscopy group had twice as many transurethral resections (55 versus 26 per 100 person years; p |
| Databáze: | OpenAIRE |
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