Lithium as an Adjunct in the Treatment of Major Depression
| Autor: | E. Horn, Y D Lapierre, Pavel D. Hrdina, M. Browne |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Bipolar Disorder Lithium (medication) Lithium Placebo Gastroenterology law.invention chemistry.chemical_compound Pharmacotherapy Double-Blind Method Lithium Carbonate Randomized controlled trial law Internal medicine Humans Medicine Pharmacology (medical) Depression (differential diagnoses) Randomized Controlled Trials as Topic Psychiatric Status Rating Scales Depressive Disorder business.industry Lithium carbonate Antidepressive Agents Clinical trial Psychiatry and Mental health chemistry Antidepressant Drug Therapy Combination business medicine.drug |
| Zdroj: | International Clinical Psychopharmacology. 5:103-110 |
| ISSN: | 0268-1315 |
| Popis: | This paper reports a double-blind cross-over study (1) to investigate the efficacy of lithium carbonate to produce rapid relief of major depression in patients who were previously unresponsive to at least 4 weeks of antidepressant therapy; (2) to study the effect of acute lithium administration on antidepressant blood levels. In contrast to other studies, lithium was found to be no more effective than placebo. The effect of lithium adjunct on antidepressant levels was not significant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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