A compact instrument to measure perfusion of vasculature in transplanted maxillofacial free flaps
| Autor: | Noah J. Kolodziejski, Urmi Parikh, Mary Ann Mycek, James F. Christian, Matthew J. Podolsky, Daniel R. McAdams, Christopher J. Stapels, Mark Vartarian, Seung Yup Lee, Stephen E. Feinberg, Dana Farkas, Daniel E. Fernandez, Brent B. Ward |
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| Rok vydání: | 2016 |
| Předmět: |
business.industry
Diffuse correlation spectroscopy Free flap 01 natural sciences Article eye diseases Microcirculation 010309 optics Transplantation Neovascularization 03 medical and health sciences surgical procedures operative 0302 clinical medicine 0103 physical sciences Medicine medicine.symptom business Perfusion 030217 neurology & neurosurgery Biomedical engineering |
| Zdroj: | SPIE Proceedings. |
| ISSN: | 0277-786X |
| Popis: | The vascularization and resulting perfusion of transferred tissues are critical to the success of grafts in buried free flap transplantations. To enable long-term clinical monitoring of grafted tissue perfusion during neovascularization and endothelialization, we are developing an implantable instrument for the continuous monitoring of perfusion using diffuse correlation spectroscopy (DCS), and augmented with diffuse reflectance spectroscopy (DRS). This work discusses instrument construction, integration, and preliminary results using a porcine graft model. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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