Cardiovascular risk factors in patients with spondyloarthritis from Northern European and Mediterranean countries: An ancillary study of the ASAS-COMOSPA project

Autor: Maxime Dougados, Helena Marzo-Ortega, Ruxandra Elena Schiotis, Pilar Font-Ugalde, Asas-Comospa task force, M. Carmen Castro-Villegas, Eduardo Collantes-Estevez, Anna Molto, Jerusalem Calvo-Gutiérrez, Salih Ozgocmen, Yolanda Jimenez-Gomez, Clementina López-Medina, Floris A. van Gaalen
Rok vydání: 2018
Předmět:
Male
Internationality
Myocardial Ischemia
Comorbidity
Disease
030204 cardiovascular system & hematology
Logistic regression
Severity of Illness Index
0302 clinical medicine
Prevalence
Cardiovascular risk factors
Sociodemographic characteristics
Framingham Risk Score
Mediterranean Region
Smoking
Middle Aged
Prognosis
Cardiovascular disease
Europe
Cardiovascular Diseases
Hypertension
Cohort
Female
Information Systems
Adult
medicine.medical_specialty
Risk Assessment
03 medical and health sciences
Age Distribution
Rheumatology
Internal medicine
Spondylarthritis
Spondyloarthritis
medicine
Humans
Obesity
Sex Distribution
Risk factor
Dyslipidemias
030203 arthritis & rheumatology
business.industry
Type 2 Diabetes Mellitus
medicine.disease
Cross-Sectional Studies
Socioeconomic Factors
Physical therapy
business
Dyslipidemia
Zdroj: Joint Bone Spine, 85(4), 447-453
ISSN: 1297-319X
Popis: Objectives: The objectives of this study were: (1) to compare the prevalence of cardiovascular disease and cardiovascular risk factors among different phenotypes of spondyloarthritis (SpA); (2) to assess the differences in cardiovascular disease and cardiovascular risk factors between two geographical areas, i.e. Northern Europe vs. Mediterranean region; (3) to identify potential predictive factors for high Framingham Risk Score regarding disease features in SpA and geographical area. Methods: Ancillary analysis of the international, multicentric, observational, cross-sectional ASAS-COMOSPA study. Cardiovascular disease and cardiovascular risk factors were compared depending on SpA phenotype and geographical regions. Potential factors associated with higher cardiovascular risk (i.e. Framingham Risk Score) were determined by a multiple logistic regression. Results: The most frequent cardiovascular risk factor and cardiovascular disease were smoking (31.2%) and ischemic heart disease (3.2%), respectively. Regarding SpA phenotype, axial SpA patients showed significantly lower prevalence (P < 0.05) of hypertension (19.2% vs. 33.8% vs. 26.6% for axial, peripheral and mixed phenotypes, respectively), type 2 diabetes mellitus (4.3% vs. 8.5% vs. 7.4%), dyslipidemia (13.9% vs. 28.4% vs. 15.2%) and ischemic heart disease (2.4% vs. 7.0% vs. 3.2%). Regarding geographical area, a higher frequency of hypertension (34.7% vs. 19.4%,), dyslipidemia (19.3% vs. 14.4%), obesity (29.3% vs. 20.7%) and ischemic heart disease (6.2% vs. 1.8%) was observed for Northern Europe vs. Mediterranean Region, respectively. Conclusions: Our results suggest that SpA phenotype and geographical area are associated with the prevalence of cardiovascular risk factors and the cardiovascular risk itself, observed in patients in the ASAS-COMOSPA cohort.
Databáze: OpenAIRE
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