Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: A review
| Autor: | S. Suresh Kumar, Anita Mirarmandi, Amira Abubakar, Ummu Bisyarah, Etel Faradjeva, Teeshalini Kudaiyappan, Tan Chuan Sean, J. Lavanya Agnes Angalene, Antony V. Samrot, Hawwa Hashma Ali |
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| Rok vydání: | 2020 |
| Předmět: |
food.ingredient
Polyesters Biocompatible Materials Nanotechnology 02 engineering and technology Biochemistry Gelatin Polyhydroxyalkanoates Chitosan 03 medical and health sciences chemistry.chemical_compound Biopolymers Drug Delivery Systems food Tissue engineering Polysaccharides Structural Biology Humans Molecular Biology 030304 developmental biology chemistry.chemical_classification Drug Carriers 0303 health sciences Tissue Engineering Proteins General Medicine Polymer 021001 nanoscience & nanotechnology chemistry Drug delivery Nanocarriers 0210 nano-technology Macromolecule |
| Zdroj: | International Journal of Biological Macromolecules. 165:3088-3105 |
| ISSN: | 0141-8130 |
| DOI: | 10.1016/j.ijbiomac.2020.10.104 |
| Popis: | Chitosan, collagen, gelatin, polylactic acid and polyhydroxyalkanoates are notable examples of biopolymers, which are essentially bio-derived polymers produced by living cells. With the right techniques, these biological macromolecules can be exploited for nanotechnological advents, including for the fabrication of nanocarriers. In the world of nanotechnology, it is highly essential (and optimal) for nanocarriers to be biocompatible, biodegradable and non-toxic for safe in vivo applications, including for drug delivery, cancer immunotherapy, tissue engineering, gene delivery, photodynamic therapy and many more. The recent advancements in understanding nanotechnology and the physicochemical properties of biopolymers allows us to modify biological macromolecules and use them in a multitude of fields, most notably for clinical and therapeutic applications. By utilizing chitosan, collagen, gelatin, polylactic acid, polyhydroxyalkanoates and various other biopolymers as synthesis ingredients, the 'optimal' properties of a nanocarrier can easily be attained. With emphasis on the aforementioned biological macromolecules, this review presents the various biopolymers utilized for nanocarrier synthesis along with their specific synthetization methods. We further discussed on the characterization techniques and related applications for the synthesized nanocarriers. |
| Databáze: | OpenAIRE |
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