The Enzymatic Activities and NBT Reduction Test of Granulocytes in Untreated and Dialysed Uraemic Patients
| Autor: | W. Sutowicz, Z. Komorowska, Zygmunt Hanicki, Tadeusz Cichocki, O. Smoleński |
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| Rok vydání: | 1979 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Neutrophils Acid Phosphatase Tetrazolium Salts Renal Dialysis Internal medicine medicine Humans Lymphocytes Reduction test chemistry.chemical_classification biology Nitroblue Tetrazolium fungi Acid phosphatase Hematology General Medicine Middle Aged Alkaline Phosphatase Endocrinology Enzyme Peroxidases chemistry biology.protein Kidney Failure Chronic Alkaline phosphatase Female Dialysis (biochemistry) Granulocytes Peroxidase |
| Zdroj: | Acta Haematologica. 61:144-149 |
| ISSN: | 1421-9662 0001-5792 |
| DOI: | 10.1159/000207647 |
| Popis: | It was found that neutrophils in untreated uraemic patients as well as in subjects on regular dialysis treatment displayed higher activity of acid phosphatase, alkaline phosphatase and peroxidase. Spontaneous reduction of nitro blue tetrazolium (NBT) by granulocytes was also higher in both groups in comparison to controls. Stimulation with latex particles gave similar results of NBT reduction in investigated patients and controls. Lymphocytes also showed an increase in acid phosphatase activity if compared to healthy persons. It seems possible that granulocytes which take part in unspecific defense mechanisms are more active in uraemic patients due perhaps to subclinical infections. |
| Databáze: | OpenAIRE |
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