B2-Microglobulin and Associated Amyloidosis Presenting as Bilateral Popliteal Tumors
| Autor: | Aviva Hopkovitz, Meyer D. Lifschitz, Woody Reese |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Male
Amyloid Pathology medicine.medical_specialty Beta-2 microglobulin business.industry Amyloidosis medicine.medical_treatment Disease medicine.disease Specific antibody Renal Dialysis Nephrology medicine Humans Knee Hemodialysis Joint Diseases Differential diagnosis beta 2-Microglobulin business Pathological Aged |
| Zdroj: | American Journal of Kidney Diseases. 12:323-325 |
| ISSN: | 0272-6386 |
| DOI: | 10.1016/s0272-6386(88)80228-2 |
| Popis: | Chronic hemodialysis has led to the prolongation of life in many patients with end-stage renal disease, but has also allowed for the development of new diseases that are a consequence of this clinical setting. B 2 -Microglobulin accumulation leading to systemic amyloidosis may be the most recent disease in this category. This case report documents the development of bilateral popliteal tumors in a patient undergoing chronic hemodialysis for 9 years. Removal of one of the tumors and pathological examination demonstrated amyloid that was positive for B2microglobulin by specific antibody testing. This case adds further support to the suggestion that B 2 -Microglobulin amyloidosis in chronic hemodialysis patients is truly a systemic disorder. The development of popliteal tumors, particularly in proximity to joints, in a chronic hemodialysis patient, must include amyloidosis in the differential diagnosis. |
| Databáze: | OpenAIRE |
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