Foveal Avascular Zone in Normal Tension Glaucoma Measured by Optical Coherence Tomography Angiography
| Autor: | Vesna Jaksic, Svetlana Jovanovic, Predrag Jovanovic, Maja Zivkovic, Mladjan Golubović, Marija Radenkovic, Sanja Sefic Kasumovic, Volkan Dayanir, Marko Zlatanovic, Gordana Zlatanović, Tolga Kocatürk |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Article Subject genetic structures lcsh:Medicine General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Maximum diameter Ophthalmology Normal tension glaucoma medicine Humans In patient Macula Lutea Low Tension Glaucoma Fluorescein Angiography Aged Observer Variation General Immunology and Microbiology business.industry lcsh:R Healthy subjects Retinal Vessels General Medicine Optical coherence tomography angiography Foveal avascular zone Middle Aged eye diseases 030104 developmental biology 030221 ophthalmology & optometry Female Tomography sense organs business Tomography Optical Coherence Horizontal diameter Research Article |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2017 (2017) |
| ISSN: | 2314-6141 2314-6133 |
| Popis: | Aim. To measure diameter of foveal avascular zone (FAZ), FAZ area, and vessel density using Optical Coherence Tomography Angiography (OCT-A) in patients with normal tension glaucoma (NTG) and to establish the possible role of OCT-A in diagnosis and follow-up of patients with NTG. Methods. Twenty-one eyes of 21 patients with NTG and 30 eyes of 30 healthy subjects underwent complete ophthalmic examination as well as OCT-A on ZEISS AngioPlex. 3×3 macula scans were used to measure vertical, horizontal, and maximum diameter of FAZ by two graders. Mean values and interobserver variability were analyzed. Image J was used for analysis of FAZ area and vessel density. Results. Mean vertical diameter (t=5.58, p<0.001), horizontal diameter (t=3.59, p<0.001), maximum diameter (t=5.94, p<0.001), and FAZ area (t=5.76, p<0.001) were statistically significantly enlarged in the NTG group compared to those in the control group. Vessel density (t=-5.80, p<0.001) was statistically significantly decreased in the NTG group compared to that in the control group. Conclusion. OCT-A could have an important role in the future in diagnosis of patients with NTG. In patients with NTG, there is larger FAZ area, while the vessel density is reduced in comparison to the control group. |
| Databáze: | OpenAIRE |
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