Solitary fibrous tumor of the tongue: Report of a case with immunohistochemical and ultrastructural studies
| Autor: | Sang Ling Wu, Fred J. Clubb, Russell Vang, John H. Connelly |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Solitary fibrous tumor
Pathology medicine.medical_specialty CD34 Fibroma Biology Pathology and Forensic Medicine Tongue Biomarkers Tumor medicine Humans Aged Cell Nucleus Mesenchymal stem cell General Medicine Anatomy medicine.disease Immunohistochemistry Neoplasm Proteins Tongue Neoplasms medicine.anatomical_structure Ultrastructure Female Desmin Endoplasmic Reticulum Rough Differential diagnosis |
| Zdroj: | Annals of Diagnostic Pathology. 6:168-171 |
| ISSN: | 1092-9134 |
| DOI: | 10.1053/adpa.2002.33903 |
| Popis: | Solitary fibrous tumors are rare in extrapleural sites and extremely rare in the oral cavity. We report a case of a solitary fibrous tumor arising from the tongue of a 70-year-old woman. The tumor measured 1.6 cm in maximum diameter and consists of spindle-shaped cells distributed in a haphazard pattern. Immunohistochemical studies show strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed. Ann Diagn Pathol 6: 168-171, 2002. |
| Databáze: | OpenAIRE |
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