Selective synthesis of (1H-benzo[d]imidazol-2-yl)(phenyl)methanone and quinoxaline from aromatic aldehyde and o-phenylenediamine
| Autor: | Pengbo Jiang, Xinfeng Cui, Haojie Ma, Zhenzhen Zhan, Guosheng Huang, Yixin Zhang, Jinghong Pu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry Sulfur Aldehyde Medicinal chemistry 0104 chemical sciences chemistry.chemical_compound Quinoxaline chemistry o-Phenylenediamine Physical and Theoretical Chemistry |
| Zdroj: | Organicbiomolecular chemistry. 17(20) |
| ISSN: | 1477-0539 |
| Popis: | We have designed a general, inexpensive, and versatile method for the synthesis of (1H-benzo[d]imidazol-2-yl)(phenyl)methanone and the formation of C-N bonds via an aromatic aldehyde and o-phenylenediamine. In the presence of N,N-dimethylformamide/sulfur, (1H-benzo[d]imidazol-2-yl)(phenyl)methanone was obtained; however, in the absence of sulfur, quinoxaline was obtained in 1,4-dioxane. A wide range of quinoxalines and (1H-benzo[d]imidazol-2-yl)(phenyl)methanones was obtained under mild conditions. |
| Databáze: | OpenAIRE |
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