Jaw osteonecrosis management around a dental implant inserted 2 years before starting treatment with zoledronic acid
| Autor: | Alberto Jiménez-Burkhardt, Ana-Belén Marín-Fernández, Blas García Medina, Antonio Aguilar-Salvatierra, Gerardo Gómez-Moreno |
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| Přispěvatelé: | [Marín-Fernández,AB, García Medina,B] Oral and Maxillofacial Surgery Service, Virgen de las Nieves University Hospital, Granada, Spain. [Aguilar-Salvatierra,A] Faculty of Dentistry, University of Granada, Granada, Spain. [Jiménez-Burkhardt,A, Gómez-Moreno,G] Department of Special Care in Dentistry, Faculty of Dentistry, University of Granada, Granada, Spain. |
| Rok vydání: | 2015 |
| Předmět: |
Peri-implantitis
Bone disease medicine.medical_treatment Difosfonatos Dentistry Case Report Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] Dental implant Chemicals and Drugs::Organic Chemicals::Organophosphorus Compounds::Diphosphonates [Medical Subject Headings] Implantes dentales Anatomy::Cells::Connective Tissue Cells::Macrophages::Osteoclasts [Medical Subject Headings] Imidazoles Osteonecrosis Bisphosphonates Diseases::Neoplasms [Medical Subject Headings] CIENCIAS MÉDICAS [UNESCO] Ciencias de la salud Neoplasias Humanos medicine.anatomical_structure Neoplasias de la mama Chemicals and Drugs::Biomedical and Dental Materials::Dental Materials::Dental Implants [Medical Subject Headings] UNESCO::CIENCIAS MÉDICAS Maxillectomy Diseases::Stomatognathic Diseases::Mouth Diseases::Peri-Implantitis [Medical Subject Headings] Oral Surgery Resorción ósea medicine.drug medicine.medical_specialty Odontología Diseases::Musculoskeletal Diseases::Bone Diseases::Osteonecrosis [Medical Subject Headings] Bone resorption Breast cancer Osteoclast Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Azoles::Imidazoles [Medical Subject Headings] medicine Periimplantitis General Dentistry Zoledronic acid Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms [Medical Subject Headings] Osteonecrosis of the jaw business.industry Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Bone Remodeling::Bone Resorption [Medical Subject Headings] Osteoclastos medicine.disease Surgery Check Tags::Female [Medical Subject Headings] business |
| Zdroj: | Marín Fernández, A.B. ; García Medina, Blas ; Aguilar Salvatierra, Antonio ; Jiménez Burkhardt, Alberto ; Gómez Moreno, Gerardo. Jaw osteonecrosis management around a dental implant inserted 2 years before starting treatment with zoledronic acid. En: Journal of Clinical and Experimental Dentistry, 2015, Vol. 7, No. 3: 444-446 RODERIC. Repositorio Institucional de la Universitat de Valéncia instname Journal of Clinical and Experimental Dentistry |
| ISSN: | 1989-5488 |
| DOI: | 10.4317/jced.52234 |
| Popis: | Journal Article; Bisphosphonates (BP) are a type of drug known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and so bone resorption. BPs are widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw (ONJ). Zoledronic acid (ZA) is an intravenous BP used in the treatment and prophylaxis of bone disease in patients with malignant tumors with bone implication. ZA is the most potent BP in clinical development. This report describes the case of a 62-year-old woman with breast cancer antecedents which relapsed, who had received a maxillary dental implant two years before the start of therapy with zoledronic acid. She later developed osteonecrosis of the jaw (ONJ), which began in the peri-implant area, and was treated for stage 3 ONJ by sub-total maxillectomy. Key words:Bisphosphonates, zoledronic acid, osteonecrosis of the jaw, peri-implantitis, maxillectomy. Yes |
| Databáze: | OpenAIRE |
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