Demethylation of 2,4-dimethoxyquinolines: the synthesis of atanine

Autor:	Philip J. Whitfield, Xavier Roset, Keith Jones, Sharon Rossiter
Rok vydání:	2003
Předmět:	Molecular Structure Stereochemistry Alkaloid Organic Chemistry Quinoline General Medicine Quinolones Biochemistry Methylation chemistry.chemical_compound chemistry Models Chemical Quinolines Organic chemistry Physical and Theoretical Chemistry Demethylation
Zdroj:	Organicbiomolecular chemistry. 1(24)
ISSN:	1477-0520
Popis:	The synthesis of the quinoline alkaloid atanine 6, by selective demethylation of the 2,4-dimethoxyquinoline 11 is presented. An alternative demethylation utilising a thiolate anion leads to the regioisomeric 4-hydroxyquinoline 13.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7813b465f75cc49cce8dc34421084ad8 https://pubmed.ncbi.nlm.nih.gov/14685309 Zobrazit plný text záznamu