Health-related quality of life and anemia in hospitalized patients with heart failure
| Autor: | I. H. Kraai, van Dirk Veldhuisen, Hans L. Hillege, Trijntje Jaarsma, Marie Louise Luttik, R.M. De Jong, Peter Johansson |
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| Přispěvatelé: | Nursing Diagnostics, Life Course Epidemiology (LCE), Cardiovascular Centre (CVC), Groningen Kidney Center (GKC) |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
DARBEPOETIN-ALPHA Placebo-controlled study health status PLACEBO-CONTROLLED TRIAL ziekenhuisopname law.invention DOUBLE-BLIND Quality of life Randomized controlled trial law hemic and lymphatic diseases Aged 80 and over hartfalen anemie Iron deficiency ASSOCIATION Middle Aged anemia IRON-DEFICIENCY RELIABILITY Female bejaarden Cardiology and Cardiovascular Medicine medicine.drug hospitalization ERYTHROPOIETIN medicine.medical_specialty Anemia QUESTIONNAIRE Internal medicine Diabetes mellitus medicine Humans Hemoglobin VALIDITY Aged gezondheidsstatus Heart Failure Relationship business.industry Patient-related outcomes medicine.disease Health-status measurements heart failures quality of life Erythropoietin Heart failure Physical therapy business kwaliteit van leven |
| Zdroj: | International Journal of Cardiology, 161(3), 151-155. Elsevier Ireland Ltd International Journal of Cardiology, 161(3), 151-155. ELSEVIER IRELAND LTD |
| ISSN: | 1874-1754 0167-5273 |
| Popis: | Background: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.Methods: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.Results: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).Conclusion: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health. (C) 2012 Elsevier Ireland Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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