Evaluation of femtosecond laser-assisted anterior capsulotomy in the presence of ophthalmic viscoelastic devices (OVDs)
| Autor: | Yoke Rung Wong, Hassan Mansoor, Yu-Chi Liu, Nyein Chan Lwin, Xin Y. Seah, Jodhbir S. Mehta |
|---|---|
| Přispěvatelé: | School of Materials Science and Engineering |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Materials science genetic structures Anterior Chamber Swine Science medicine.medical_treatment Cataract Extraction 01 natural sciences Article Viscoelasticity 010309 optics 03 medical and health sciences 0302 clinical medicine Lens Implantation Intraocular Ophthalmology Translational Research 0103 physical sciences medicine Animals Hyaluronic Acid Anterior capsulotomy Phacoemulsification Multidisciplinary Keratectomy Subepithelial Laser-Assisted Materials [Engineering] Viscosity Aqueous humour Lasers Optical Devices Capsule Translational research Cataract surgery Laser assisted Femtosecond 030221 ophthalmology & optometry Capsulotomy Medicine Surgery Laser Therapy |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-78361-8 |
| Popis: | The introduction of femtosecond laser-assisted cataract surgery is an alternative approach to conventional cataract surgery. Our study aimed to determine the effectiveness of femtosecond laser-assisted capsulotomy in the presence of different ophthalmic viscoelastic devices (OVDs) in the anterior chamber. Fresh porcine eyes (n = 96) underwent LDV Z8-assisted anterior capsulotomy, either in the presence of an OVD (Viscoat, Provisc, Healon, Healon GV or HPMC) or without, using 90% and 150% energies respectively. Following that, the capsule circularity, tag's arc-length, tag-length, tag-area and rupture strength (mN) of the residual capsular bag were evaluated. We found that increasing energy from 90 to 150% across the OVD sub-groups improved the studied capsulotomy parameters. Amongst the 90% energy sub-groups, the circularity and tag-parameters were worse with Viscoat and Healon GV, which have higher refractive index and viscosity compared to the aqueous humour. Using 150% energy, Healon GV showed a significantly worse total arc-length (p = 0.01), total tag-length (p = 0.03) and total tag-area (p = 0.05) compared to the control group. We concluded that; an OVD with a refractive index similar to aqueous humour and lower viscosity, such as Healon or Provisc, as well as a higher energy setting, are recommended, to enhance the efficacy of laser capsulotomy. National Medical Research Council (NMRC) National Research Foundation (NRF) Published version This research was supported by the Singapore National Research Foundation under its Translational and Clinical Research (TCR) programme (NMRC/TCR/1021-SERI/2013), and by Duke-NUS Medical School, Singapore under its Academia Clinical Programme (ACP) (R1396/82/2016). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|