Intraamniotic digoxin administration versus intracardiac or funic potassium chloride administration to induce foetal demise before termination of pregnancy: a prospective study
| Autor: | Münip Akalın, Oya Demirci, Oya Gokcer, Hayal İsmailov, Ali Sahap Odacilar, Gizem Elif Dizdarogulları, Özge Kahramanoğlu, Aydın Ocal, Guher Bolat, Mucize Eriç Özdemir |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Obstetrics and Gynaecology. 42:3477-3483 |
| ISSN: | 1364-6893 0144-3615 |
| DOI: | 10.1080/01443615.2022.2144173 |
| Popis: | Different foeticide techniques and pharmacological agents have been used to achieve foetal asystole. This study aimed to compare the success of intraamniotic digoxin, intracardiac potassium chloride (KCl), and funic KCl in achieving foetal asystole and discuss procedural difficulties for physicians and clinical outcomes. This prospective observational study included 124 patients who received foeticide at 22-31 weeks of gestation. All procedures were performed transabdominally, and 1 mg of intraamniotic digoxin, funic KCl, or intracardiac KCl was administered. Procedure times, procedural difficulty scores, patient pain scores, decrease in haematocrit levels, induction and hospitalisation times, and the presence of chorioamnionitis were recorded. The foeticide success rates were 93.0, 95.1, and 97.5% for intraamniotic digoxin, intracardiac KCl, and funic KCl, respectively. Intraamniotic digoxin was associated with shorter procedure times, lower procedural difficulty scores, and lower patient pain scores ( |
| Databáze: | OpenAIRE |
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