Miniaturized sensor for electroanalytical and electrochemiluminescent detection of pathogens enabled through laser-induced graphene electrodes embedded in microfluidic channels

Autor:	Florian Gerstl, Uma Pongkitdachoti, Fuangfa Unob, Antje J. Baeumner
Rok vydání:	2022
Předmět:	Drinking Water Lasers Microfluidics Biomedical Engineering Cryptosporidiosis Cryptosporidium Bioengineering Biosensing Techniques DNA Electrochemical Techniques General Chemistry Biochemistry Soil Liposomes Luminescent Measurements Organometallic Compounds Humans Graphite Electrodes
Zdroj:	Lab on a Chip. 22:3721-3733
ISSN:	1473-0189 1473-0197
DOI:	10.1039/d2lc00593j
Popis:	High performance, laser-induced graphene (LIG) electrodes were integrated into adhesive tape-based microfluidic channels to realize both electrochemical (EC) and electrochemiluminescent (ECL) detection approaches. This provides strategies for low limits of detection, simple hardware requirements and inexpensive fabrication, which are characteristics required for assays in the competitive point-of-care (POC) sensor field. Here, electrode design and microchannel dimensions were studied and a DNA hybridization assay with liposomes for signal amplification was developed for the specific detection of DNA derived from
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fbb585ee81636c8a7321e0f339397c https://doi.org/10.1039/d2lc00593j Zobrazit plný text záznamu