Propofol versus midazolam for procedural sedation in the emergency department: A study on efficacy and safety
| Autor: | Ewoud ter Avest, Femke Beije, Rieneke A. Feenstra, Maike G.E. Bosch, Heleen Lameijer, Ytje T. Sikkema, Bas W.J. Bens, Albert Pol |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.drug_class Sedation Midazolam ANTERIOR SHOULDER DISLOCATION Conscious Sedation Patient characteristics Pain EVENTS 03 medical and health sciences Patient safety ANALGESIA 0302 clinical medicine medicine Humans Hypnotics and Sedatives 030212 general & internal medicine Emergency Treatment Propofol Aged Netherlands Pain Measurement Retrospective Studies Aged 80 and over business.industry 030208 emergency & critical care medicine Retrospective cohort study General Medicine Emergency department Middle Aged REDUCTION Treatment Outcome Sedative Anesthesia Emergency Medicine Female Patient Safety medicine.symptom business medicine.drug |
| Zdroj: | American journal of emergency medicine, 35(5), 692-696. ELSEVIER SCIENCE INC |
| ISSN: | 0735-6757 |
| Popis: | Background: Procedural sedation for painful procedures in the emergency department (ED) can be accomplished with various pharmacological agents. The choice of the sedative used is highly dependent on procedure- and patient characteristics and on personal- or local preferences.Methods: We conducted a multicenter retrospective cohort study of procedural sedations performed in the EDs of 5 hospitals in the Netherlands over a 4 year period to evaluate the efficacy- (success rate of the intended procedure) and safety (incidence of sedation (adverse) events) of propofol sedations compared to midazolam sedations.Results: A total of 592 ED sedations were included in our study. Patients sedated with propofol (n = 284, median dose 75 mg) achieved a deeper level of sedation (45% vs. 25% deep sedation, p Conclusion: Propofol is more effective and at least as safe as midazolam for procedural sedation in the ED. (C) 2017 Elsevier Inc. All rights reserved. |
| Databáze: | OpenAIRE |
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