Recurrent Invasive Thymoma with Pleural Dissemination: Disease Management and Treatment Possibilities
| Autor: | Esther Willemse, Guy Andry, Y Lefebvre, J Konecna, R. de Wind |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Thymoma Biopsy Pleural Neoplasms hemic and lymphatic diseases medicine Recurrent disease Humans Neoplasm neoplasms medicine.diagnostic_test business.industry Disease Management Thymus Neoplasms General Medicine Middle Aged Invasive thymoma Thymectomy medicine.disease Surgery First line treatment Masaoka Stage IVb Neoplasm Recurrence Local Tomography X-Ray Computed Who classification business |
| Zdroj: | Europe PubMed Central |
| ISSN: | 0001-5458 |
| DOI: | 10.1080/00015458.2014.11681028 |
| Popis: | Thymoma is the most common benign neoplasm of the anterior mediastinum presenting often an agressive behaviour typical for the malignants tumors. The rate of invasive thymoma recurrency is relatively high. We present the case of a 55-year old man with a recurrent invasive thymoma with a pleural dissemination, detected on CT-imaging 2 years following his primary surgery. Since the first pre-operative imaging studies showed no invasion of the adjacent organs and a thymoma was suspected, a surgical resection was decided as a first line treatment. Per-operatively a number of adjacent structures were invaded and despite a macroscopical RO resection, the margins were microscopically positive. An invasive thymoma, WHO classification B3, Masaoka stage IVb was diagnosed and the patient received adjuvant radiotherapy. We highlight the role of multimodality treatement and disscus the potential of surgical, radiotherapeutical and systemic therapy in stage IV thymoma as well as in recurrent disease. |
| Databáze: | OpenAIRE |
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