Fate of haem iron in the malaria parasite Plasmodium falciparum
| Autor: | Pete Smith, Joanne Egan, Donelly A. van Schalkwyk, Giovanni R. Hearne, Jason C. Walden, Dale Taylor, B. Trevor Sewell, Jill M. Combrinck, Helder M. Marques, Timothy J. Egan, Skhumbuzo Ntenteni |
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| Rok vydání: | 2002 |
| Předmět: |
Hemeproteins
biology Chemistry Iron Plasmodium falciparum Heme Cell Biology medicine.disease biology.organism_classification Biochemistry Microbiology Spectroscopy Mossbauer chemistry.chemical_compound parasitic diseases Heme metabolism Food vacuole medicine Animals Parasite hosting Molecular Biology Malaria Research Article |
| Zdroj: | Biochemical Journal. 365:343-347 |
| ISSN: | 1470-8728 0264-6021 |
| Popis: | Chemical analysis has shown that Plasmodium falciparum trophozoites contain 61±2% of the iron within parasitized erythrocytes, of which 92±6% is located within the food vacuole. Of this, 88±9% is in the form of haemozoin. 57Fe-Mössbauer spectroscopy shows that haemozoin is the only detectable iron species in trophozoites. Electron spectroscopic imaging confirms this conclusion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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