| Autor: |
M, Atif, Atif, Hanif, M S, AlSalhi, S, Devanesan, Haya Abdulaziz, Altamimi |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Saudi Journal of Biological Sciences. 29:103304 |
| ISSN: |
1319-562X |
| DOI: |
10.1016/j.sjbs.2022.103304 |
| Popis: |
In this study, the blood volume and oxygen saturation of tumors were measured after photoacoustic imaging (PAI) under conditions of pre-photodynamic therapy (PDT), post-PDT, and 4 hrs, and 24 hrs post-PDT. PDTs with aminolevulinic acid (ALA) and low and high doses of benzoporphyrin derivative (BPD) were conducted to observe oxygen saturation changes, and the rapid oxygen consumption in the blood detected due to the action of BPD at the vascular level resulted in the recovery of PDT completion. Likewise, blood volume changes followed by ALA-PDT and BPD-PDT at low and high doses depicted a fast expansion of the blood volume after treatment. The tumor subjected to a high dose of ALA-PDT showed a partial alteration of Hb-pO |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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