An integrated flex-microfluidic-Si chip device towards sweat sensing applications
Autor: | den Jmj Jaap Toonder, Ajh Arjan Frijns, M.A.G. Zevenbergen, C Chuan Nie |
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Přispěvatelé: | Microsystems, Group Den Toonder, Institute for Complex Molecular Systems |
Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Materials science
Silicon Microfluidics Integration chemistry.chemical_element Nanotechnology Flexible devices 02 engineering and technology 01 natural sciences law.invention law Evaporative pumping Lamination Materials Chemistry Fluidics Electrical and Electronic Engineering Instrumentation Microchannel Thin layers 010401 analytical chemistry Metals and Alloys Wearable sensorsa 021001 nanoscience & nanotechnology Condensed Matter Physics Chip 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry Electrode sweat sensing 0210 nano-technology |
Zdroj: | Sensors and Actuators, B: Chemical, 227, 427-437. Elsevier |
ISSN: | 0925-4005 |
Popis: | In this work, we introduce a flexible microfluidic device with an integrated silicon sensor chip, which may in the future be developed towards a wearable device for continuous and prolonged sweat sensing. The device is made by the lamination of three thin layers of polyethylene terephthalate (PET), in which fluidic structures are created using laser microfabrication. The main fluidic structures are an inlet, a microchannel, a sensing cavity, and a porous structure as an outlet. When placed on a surface such as the skin, a filter integrated in the inlet absorbs any liquid present on the surface. Then, the liquid fills the microchannel and the sensing cavity by capillarity; specially designed filter paper structures prevent any liquid pinning or air inclusions to form during this process. Finally, when the liquid reaches the porous outlet, it evaporates via the pores, which generates a continuous flow through the device and over the sensor chip. The latter contains electrodes for electrochemical pH monitoring, and is mounted within the sensing cavity via screen-printed electrical connections. We show a proof-of-principle of the integrated device by demonstrating continuous monitoring of pH changes of liquids that are sequentially fed into the device inlet. |
Databáze: | OpenAIRE |
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