The Evolving Landscape of Gene Therapy in Plastic Surgery
| Autor: | Aspinder Singh, Edward M. Reece, Daniel K. Chang, Anjali C. Raghuram, Brent E. Schultz, Mervin Nunez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry Genomic sequencing Genetic enhancement Review article 03 medical and health sciences Plastic surgery 030104 developmental biology 0302 clinical medicine Rapid rise 030220 oncology & carcinogenesis medicine CRISPR Surgery Intensive care medicine business |
| Zdroj: | Semin Plast Surg |
| Popis: | With the rapid rise of personalized genomic sequencing and clustered regularly interspaced short palindromic repeat (CRISPR) technology, previous gaps in gene therapy are beginning to be bridged, paving the way for increasing clinical applicability. This article aims to provide an overview of the fundamentals of gene therapy and discuss future potential interventions relevant to plastic surgeons. These interventions include enhancing tissue regeneration and healing, as well as modifying disease processes in congenital anomalies. Though clinical applications are still on the horizon, a deeper understanding of these new advances will help plastic surgeons understand the current landscape of gene therapy and stay abreast of future opportunities. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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