Effectiveness of Cognitive Rehabilitation in Parkinson’s Disease: A Systematic Review and Meta-Analysis
| Autor: | Natalia Ojeda, Javier Peña, Olaia Lucas-Jiménez, Naroa Ibarretxe-Bilbao, Yolanda Balboa-Bandeira, Itsasne Sanchez-Luengos |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
cognition
Working memory Medicine (miscellaneous) Cognition Executive functions Parkinson’s disease (PD) Article 03 medical and health sciences 0302 clinical medicine Visual memory Meta-analysis Medicine Verbal fluency test 030212 general & internal medicine Cognitive rehabilitation therapy Verbal memory Psychology cognitive rehabilitation 030217 neurology & neurosurgery intervention Clinical psychology |
| Zdroj: | Journal of Personalized Medicine Volume 11 Issue 5 Journal of Personalized Medicine, Vol 11, Iss 429, p 429 (2021) |
| ISSN: | 2075-4426 |
| DOI: | 10.3390/jpm11050429 |
| Popis: | Cognitive deficits influence the quality of life of Parkinson’s disease (PD) patients. In order to reduce the impact of cognitive impairment in PD, cognitive rehabilitation programs have been developed. This study presents a systematic review and meta-analysis regarding the effectiveness of cognitive rehabilitation in non-demented PD patients. Twelve articles were selected according to PRISMA guidelines. The systematic review showed that attention, working memory, verbal memory, executive functions and processing speed were the most frequently improved domains. Meta-analysis results showed moderate effects on global cognitive status (g = 0.55) and working memory (g = 0.50) small significant effects on verbal memory (g = 0.41), overall cognitive functions (g = 0.39) and executive functions (g = 0.30) small non-significant effects on attention (g = 0.36), visual memory (g = 0.29), verbal fluency (g = 0.27) and processing speed (g = 0.24) and no effect on visuospatial and visuoconstructive abilities (g = 0.17). Depressive symptoms showed small effect (g = 0.24) and quality of life showed no effect (g = −0.07). A meta-regression was performed to examine moderating variables of overall cognitive function effects, although moderators did not explain the heterogeneity of the improvement after cognitive rehabilitation. The findings suggest that cognitive rehabilitation may be beneficial in improving cognition in non-demented PD patients, although further studies are needed to obtain more robust effects. |
| Databáze: | OpenAIRE |
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