Role of increased central arterial stiffness in macro and microvascular damage in patients with coronary artery disease

Autor: Juan Carlos, Hidalgo-Santiago, Jesús, Oneto-Otero, Alfredo, Michán-Doña, Pablo, Gomez-Fernández
Rok vydání: 2021
Předmět:
Zdroj: Clínica e Investigación en Arteriosclerosis (English Edition). 33:224-234
ISSN: 2529-9123
DOI: 10.1016/j.artere.2021.07.007
Popis: Patients with heart disease frequently have renal dysfunction manifested by a decrease in glomerular filtration rate (GFR) and / or increase of albuminuria.The objective was to study the possible role of increased aortic stiffness in the presence and extent of coronary artery disease (CAD) and kidney dysfunction in a group of patients with suspected CAD.We studied forty-eight patients undergoing coronariography for suspected coronary disease (CAD). Using applanation tonometry on the radial artery and applying a transfer function, central blood pressure values were calculated. The study of aortic stiffness was done by determining the carotid-femoral pulse velocity (PvOf the 48 patients, 11 had no significant coronary lesions, 24 showed significant lesions in 1 or 2 coronary arteries and 13 in ≥ 3 arteries. The group with a higher degree of CD had significantly higher cPP values than the group without CD. The PvIn patients with stable CD, Pv
Databáze: OpenAIRE