Incomplete cavernous sinus syndrome as the initial manifestation of a previously undetected metastatic prostate adenocarcinoma
| Autor: | María Machío Castelló, Julia Montoya Bordón, Rafael Sáez Pinel, José Miguel Villacampa Aubá, Carlos Cenjor Español, Rafael Carias Calix, Diego Escobar Montatixe |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Adenocarcinoma Skull Base Neoplasms Metastasis Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Clivus Ptosis Biopsy Mydriasis Diplopia Medicine Humans medicine.diagnostic_test business.industry Biopsy Needle Headache Prostatic Neoplasms Chemoradiotherapy Syndrome Middle Aged medicine.disease Primary tumor Immunohistochemistry Magnetic Resonance Imaging Surgery medicine.anatomical_structure Treatment Outcome Otorhinolaryngology 030220 oncology & carcinogenesis Cavernous Sinus Headaches medicine.symptom Differential diagnosis business 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Headneck. 39(7) |
| ISSN: | 1097-0347 |
| Popis: | Background Cavernous sinus syndrome presents as unilateral ophthalmoplegia associated with sympathetic denervation, pain, paresthesias, and V1 and V2 distribution numbness. The etiology may be vascular, inflammatory, infectious, and, less commonly, neoplastic (metastatic). Methods We report a patient with incomplete cavernous sinus syndrome as the initial manifestation of previously undetected metastatic prostate adenocarcinoma. Results A 59-year-old man presented with a 2-month history of left hemicranial headaches with ptosis and binocular diplopia. Clinical evaluation found left third, fourth, and sixth cranial nerve palsy with mydriasis and ptosis. An MRI showed an enhancing lesion at the clivus with infiltration of left cavernous sinus. A trans-sphenoidal biopsy was performed, leading to diagnosis of metastatic prostate adenocarcinoma. The patient underwent treatment and achieved clinical improvement. Conclusions In middle-aged men, it is important to include metastatic prostate adenocarcinoma in the differential diagnosis of cavernous sinus syndrome, even in the absence of primary tumor diagnosis. |
| Databáze: | OpenAIRE |
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