Comparison of plethysmographic and helium dilution lung volumes in patients with a giant emphysematous bulla as selection criteria for endobronchial valve implant†

Autor: Gaetana Messina, Nicola Serra, Alfonso Fiorelli, Elisabetta Frongillo, Alberto De Felice, Matteo Pierdiluca, Mario Santini, Roberto Scaramuzzi
Přispěvatelé: Fiorelli, Alfonso, Scaramuzzi, Roberto, Pierdiluca, Matteo, Frongillo, Elisabetta, Messina, Gaetana, Serra, Nicola, De Felice, Alberto, Santini, Mario
Rok vydání: 2017
Předmět:
Zdroj: European Journal of Cardio-Thoracic Surgery. 52:534-542
ISSN: 1873-734X
1010-7940
DOI: 10.1093/ejcts/ezx108
Popis: To assess whether the difference in lung volume measured with plethysmography and with the helium dilution technique could differentiate an open from a closed bulla in patients with a giant emphysematous bulla and could be used as a selection criterion for the positioning of an endobronchial valve. OBJECTIVES: To assess whether the difference in lung volume measured with plethysmography and with the helium dilution technique could differentiate an open from a closed bulla in patients with a giant emphysematous bulla and could be used as a selection criterion for the positioning of an endobronchial valve.METHODS: We reviewed the data of 27 consecutive patients with a giant emphysematous bulla undergoing treatment with an endobronchial valve. In addition to standard functional and radiological examinations, total lung capacity and residual volume were measured with the plethysmographic and helium dilution technique. We divided the patients into 2 groups, the collapse or the no-collapse group, depending on whether the bulla collapsed or not after the valves were put in position. We statistically evaluated the intergroup differences in lung volume and outcome.RESULTS: In the no-collapse group (n = 6), the baseline plethysmographic values were significantly higher than the helium dilution volumes, including total lung capacity (188 +/- 14 vs 145 +/- 13, P = 0.0007) and residual volume (156 +/- 156 vs 115 +/- 15, P = 0.001). In the collapse group, there was no significant difference in lung volumes measured with the 2 methods. A difference in total lung capacity of
Databáze: OpenAIRE